Czech scientists develop mito DFO anti-cancer agent

Published: 06.05.2021 Related countries:  Czech Republic Czech Republic

Czech scientists have developed an anti-cancer agent, mitoDFO, which targets iron’s mitochondrial metabolism.

Scientists from the Institute of Biotechnology of the Czech Academy of Sciences (AV ČR) have developed an anti-cancer agent, mitoDFO, which targets iron’s mitochondrial metabolism. It uses the fact that tumorous cells need more iron. It blocks its processes, thus preventing the tumour from growing further. The new method leads to suppressed cancerous growth and division. It causes cell death not only in vitro, i.e. in glass in the laboratory, but also in vivo. The scientists tested the agent on mouse models. It is an exclusively Czech research project; the scientists and SmartBrain have already applied for patents in the European Union and the United States.

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